Affiliations: [a] Service of Neurology, University Hospital Marqués de Valdecilla – IDIVAL (CIBERNED), Santander, Spain
| [b] Memory and Aging Center, University of California San Francisco, San Francisco, CA, USA
| [c] Nuclear Medicine Department; Molecular Imaging Group IDIVAL, University Hospital Marques de Valdecilla, University of Cantabria, Santander, Spain
Correspondence:
[*]
Correspondence to: Javier Riancho, MD, PhD, Service of Neurology, University Hospital Marqués de Valdecilla, Av Valdecilla s/n, 39008 Santander, Spain. Tel.: +34 942 202520; Fax: +34 942 201695; E-mail: javier.riancho86@gmail.com.
Abstract: Among primary progressive aphasias (PPAs), logopenic variant PPA (lv-PPA) is usually related to Alzheimer’s disease. Although it has been widely clinically and pathologically evaluated, the topography in LPA is still controversial. We report a patient presenting with a logopenic syndrome due to a strategic lesion located in the superior and middle temporal gyrus and compare our findings with those of a PiB-PET positive lv-PPA patient matched by age, gender, and education. We consider that our study provides new anatomical clues to better understand the cognitive mechanisms underlying the logopenic syndrome.
