No Differences in Hippocampal Volume between Carriers and Non-Carriers of the ApoE ε4 and ε2 Alleles in Young Healthy Adolescents

Article type: Short Communication

Authors: Khan, Wasim^{a; b; c} | Giampietro, Vincent^a | Ginestet, Cedric^{a; b} | Dell'Acqua, Flavio^{a; b; c} | Bouls, David^{a; b; c} | Newhouse, Steven^{a; b; c} | Dobson, Richard^{a; b; c} | Banaschewski, Tobias^{d; e} | Barker, Gareth J.^a | Bokde, Arun L.W.ⁱ | Büchel, Christian^f | Conrod, Patricia^{a; h} | Flor, Herta^{d; e} | Frouin, Vincent^o | Garavan, Hugh^{r; s} | Gowland, Penny^t | Heinz, Anreas^h | Ittermann, Bernd^j | Lemaître, Hervé^k | Nees, Frauke^{d; e} | Paus, Tomas^{l; m; n} | Pausova, Zdenka^q | Rietschel, Marcella^{d; e} | Smolka, Michael N.^p | Ströhle, Andreas^h | Gallinat, Jean^h | Westman, Eric^u | Schumann, Gunther^{a; b} | Lovestone, Simon^{a; b; c} | Simmons, Andrew^{a; b; c; *} | the IMAGEN consortium ()

Affiliations: [a] King's College London, Institute of Psychiatry, London, UK | [b] NIHR Biomedical Research Centre for Mental Health, King's College London, London, UK | [c] NIHR Biomedical Research Unit for Dementia, King's College London, London, UK | [d] Central Institute of Mental Health, Mannheim, Germany | [e] Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Germany | [f] Universitaetsklinikum Hamburg Eppendorf, Hamburg, Germany | [g] Department of Psychiatry, Universite de Montreal, CHU Ste Justine Hospital, Montreal, Canada | [h] Department of Psychiatry and Psychotherapy, Campus Charité Mitte, Charité–Universitätsmedizin Berlin, Berlin, Germany | [i] Institute of Neuroscience and Discipline of Psychiatry, School of Medicine, Trinity College Dublin, Dublin, Ireland | [j] Physikalisch-Technische Bundesanstalt (PTB), Braunschweig und Berlin, Berlin, Germany | [k] Institut National de la Santé et de la Recherche Médicale, INSERM CEA Unit 1000 “Imaging & Psychiatry”, University Paris Sud, Orsay, and AP-HP Department of Adolescent Psychopathology and Medicine, Maison de Solenn, University Paris Descartes, Paris, France | [l] Rotman Research Institute, University of Toronto, Toronto, Canada | [m] School of Psychology, University of Nottingham, Nottingham, UK | [n] Montreal Neurological Institute, McGill University, Montreal, Canada | [o] Neurospin, Commissariat à l'Energie Atomique et aux Energies Alternatives, Paris, France | [p] Neuroimaging Center, Department of Psychiatry and Psychotherapy, Technische Universität Dresden, Germany | [q] The Hospital for Sick Children, University of Toronto, Toronto, Canada | [r] Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland | [s] Departments of Psychiatry and Psychology, University of Vermont, Burlington, VT, USA | [t] School of Physics and Astronomy, University of Nottingham, Nottingham, UK | [u] Karolinska Institute, Stockholm, Sweden

Correspondence: [*] Correspondence to: Dr. Andrew Simmons, Department of Neuroimaging, Institute of Psychiatry, King's College London, De Crespigny Park, London SE5 8AF, UK. Tel.: +44 20 3228 3055; Fax: +44 20 3228 2116; E-mail: andy.simmons@kcl.ac.uk.

Keywords: Apolipoprotein E, hippocampal volume, magnetic resonance imaging, young healthy adolescents

DOI: 10.3233/JAD-131841

Journal: Journal of Alzheimer's Disease, vol. 40, no. 1, pp. 37-43, 2014