Recent Advances in Imaging Alzheimer's Disease

Issue title: Alzheimer's Disease: Advances for a New Century

Guest editors: George Perry, Xiongwei Zhu, Mark A. Smith, Aaron Sorensen and Jesús Avila

Article type: Review Article

Authors: Braskie, Meredith N. | Toga, Arthur W. | Thompson, Paul M.^{; *}

Affiliations: Laboratory of Neuro Imaging, Department of Neurology, UCLA School of Medicine, Los Angeles, CA, USA

Correspondence: [*] Correspondence to: Paul M. Thompson, PhD, Laboratory of Neuro Imaging, Department of Neurology, UCLA School of Medicine, 635 Charles Young Drive South, Suite 225, Los Angeles, CA 90095-7334, USA. Tel.: +1 310 206 2101; E-mail: thompson@loni.ucla.edu.

Abstract: Advances in brain imaging technology in the past five years have contributed greatly to the understanding of Alzheimer's disease (AD). Here, we review recent research related to amyloid imaging, new methods for magnetic resonance imaging analyses, and statistical methods. We also review research that evaluates AD risk factors and brain imaging, in the context of AD prediction and progression. We selected a variety of illustrative studies, describing how they advanced the field and are leading AD research in promising new directions.

Keywords: Alzheimer's disease, amyloid, imaging, magnetic resonance imaging, methods, positron emission tomography, prediction, progression, risk factors

DOI: 10.3233/JAD-2012-129016

Journal: Journal of Alzheimer's Disease, vol. 33, no. s1, pp. S313-S327, 2013