S-Adenosyl Methionine: A Natural Therapeutic Agent Effective Against Multiple Hallmarks and Risk Factors Associated with Alzheimer's Disease

Article type: Short Communication

Authors: Shea, Thomas B.^{; *} | Chan, Amy

Affiliations: Center for Cellular Neurobiology and Neurodegeneration Research, Department of Biological Sciences, UmassLowell, One University Avenue, Lowell, MA 01854, USA

Correspondence: [*] Corresponding author. Tel.: +1 978 934 2881; Fax: +1 978 934 3062; E-mail: thomas_shea@uml.edu.

Abstract: Recent preclinical and clinical findings demonstrate that dietary supplementation with S-adenosyl methionine alleviates a variety of risk factors and hallmarks associated with Alzheimer's disease. These findings support and extend prior studies, some of which are decades old, and support the notion that nutritional supplementation may represent an important augmentation for therapy in Alzheimer's disease.

DOI: 10.3233/JAD-2008-13107

Journal: Journal of Alzheimer's Disease, vol. 13, no. 1, pp. 67-70, 2008