Three-month endurance training improves functional fitness and knee muscle performance of patients with end stage renal disease (ESRD)

Article type: Research Article

Authors: Dziubek, Wioletta^{a; *} | Bulińska, Katarzyna^a | Rogowski, Ƚukasz^b | Kusztal, Mariusz^c | Zembroń-Ƚacny, Agnieszka^d | Goƚȩbiowski, Tomasz^c | Markowska, Dominika^a | Klinger, Marian^c | Woźniewski, Marek^a

Affiliations: [a] Department of Physiotherapy, University School of Physical Education, Wroclaw, Poland | [b] Non-Public Medical College of Wroclaw, Poland | [c] Department and Clinic of Nephrology and Transplantation Medicine, Wroclaw Medical University, Poland | [d] Faculty of Medicine and Health Sciences, University of Zielona, Gora, Poland

Correspondence: [*] Corresponding author: Wioletta Dziubek, Faculty of Physiotherapy, University School of Physical Education in Wroclaw, al. J. J. Paderewskiego 35, 51-612 Wroclaw, Poland. Tel.: +48 71 3473520; Fax: +48 71 3473081; E-mail:wioletta.dziubek@awf.wroc.pl, Aksamitna1974@wp.pl

Abstract: BACKGROUND: Patients with end-stage renal disease (ESRD) have poor physical performance and reduced exercise capacity due to frequent haemodialysis treatments. OBJECTIVE: The aim of the study was to determine the effectiveness of a three-month endurance training programme in patients with ESRD. METHODS: In order to improve both functional fitness and skeletal muscle properties, movement therapy-cycle ergometer, was applied in eligible ESRD patients during dialysis. The study included 40 dialysis patients, but only 27 patients completed the full three-month training during each haemodialysis treatment. Before and after training, all patients underwent observations according to the established protocol: functional capacity - Six-Min Walk Test, agility - Timed Up and Go test, and muscle strength testing under isokinetic conditions at 60, 180 and 300°/s. RESULTS: Patients covered significantly longer distances in the 6MWT with a higher gait intensity after the 3 months training programme: the 6MWT increased from 360.8 to 390.2 m and metabolic equivalent from 2.74 to 2.85. The TUG significantly decreased in both women and men: from 9.07 to 7.51 s, and from 9.64 s to 7.4 s, respectively. The knee extension peak moment at 60 and 180°/s was significantly higher in women than in men following training. In addition, the women demonstrated more significant changes in flexor muscles at all angular velocities. CONCLUSIONS: Three-month endurance training was effective in patients with ESRD in improving both functional fitness and skeletal muscle properties.

Keywords: End-stage renal disease (ESRD), 6MWT, muscle moment, physical training

DOI: 10.3233/IES-160623

Journal: Isokinetics and Exercise Science, vol. 24, no. 3, pp. 237-246, 2016