Affiliations: ECLAMC: Latin-American Collaborative Study of Congenital Malformations; WHO Collaborative Centre for the Prevention of Birth Defects; FIOCRUZ: Dept. Genetica, Instituto Oswaldo Cruz, Rio de Janeiro, Brazil | IMBICE: Instituto Multidisciplinario de Biologia Celular, La Plata, Argentina
Note: [] Correspondence to: Eduardo E. Castilla, ECLAMC/Genetica/FIOCRUZ, Caixa Postal 926, 21.040, Rio de Janeiro, Brazil.
Note: [] Paper presented during the 18th Meeting of the European Teratology Society, Edinburgh, 1990.
Abstract: Medical authorities in developing countries are primarily interested in nutritional and infectious diseases. Therefore, activities directed to the prevention and control of low priority illnesses, such as birth defects, need to be particularly effective, simple, and economical. Monitoring of congenital anomalies is one of the preventive activities which can be efficiently performed at very low cost. Guidelines for this are given, and their application exemplified by the case of Uruguay. Uruguay has recently attained an infant mortality rate of 20/1,000, with the congenital anomalies ranking as its second cause. The government of Uruguay, through the Pan American Health Organisation/World Health Organisation (PARO/WHO) called the Estudio Colaborativo Latino Americano de Malformaciones Congenitas (ECLAMC) for advice in order to plan a program for the prevention of birth defects. The recommendations given were based on conclusions drawn from the analysis of data the ECLAMC program has been accumulating, from Uruguay and other Latin-American countries, since 1967. The case of Uruguay clearly indicates that sensible guidelines for birth defects prevention can be provided, after working with this “low priority and uninteresting” group of illnesses for more than twenty years.
