A parallel feature selection algorithm for detection of cancer biomarkers

Article type: Research Article

Authors: Razmjouei, Maryam | Hamidi, Hamid Reza^*

Affiliations: Computer Engineering Department, Imam-Khomeini International University, Qazvin, Iran

Correspondence: [*] Corresponding author: Hamid Reza Hamidi, Computer Engineering Department, Imam-Khomeini International University, Qazvin, Iran. E-mail: hamidreza.hamidi@eng.ikiu.ac.ir.

Abstract: Biomarker plays an important role in early disease diagnosis including cancer. The World Health Organization defines a biomarker as any structure or process in the body that is measurable and affects the prognosis or outcome of the disease. Today, biomarkers can be identified using bioinformatics tools. The detection of biomarkers in the field of bioinformatics is considered more as a problem of feature selection. Many feature selection algorithms have been used for biomarker discovery however these algorithms do not have enough accuracy or have computational complexity. For this reason, the researchers discard the high accuracy algorithms because they are time consuming. We redesigned an efficient algorithm based on parallel algorithms. We used the Cancer Genome Atlas (TCGA) including breast cancer patients. The proposed algorithm has the same accuracy and increases the speed of algorithm.

Keywords: Biomarker, bioinformatics, breast cancer, parallel algorithm, MSVM-RFE

DOI: 10.3233/IDT-210227

Journal: Intelligent Decision Technologies, vol. 16, no. 2, pp. 441-447, 2022