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Article type: Research Article
Authors: Amini, Fatemeh Ghaeda | Nia, Anahita Fesharkia | Sharbafi, Mohammad Hosseinb | Khandari, Aydaa | Gargari, Soraya Salehc; *
Affiliations: [a] Department of Gynecology and Obstetrics, Shahid Beheshti University of Medical Sciences, Tehran, Iran | [b] Tehran University of Medical Sciences, Tehran, Iran | [c] Men’s Health and Reproductive Health Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Correspondence: [*] Corresponding author: Soraya Saleh Gargari, Feto-Maternal Unit, Shohadaye Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. E-mail: soraya_saleh2000@yahoo.co.uk.
Abstract: BACKGROUND: Gestational diabetes mellitus (GDM) is one of the prevalent adverse conditions among pregnant women which needs delicate monitoring and control. GDM is a state in which the pregnant women’s blood glucose level exceeds the normal range. Our goal was to determine the best therapeutic method to control the blood glucose level among GDM patients by comparing of the efficacy between two Insulin consisting, Novo-rapid + Levemir Insulin and Regular + NPH Insulin. METHOD: In this double-blind, randomized clinical trial study, we enrolled 100 women with GDM as an inpatient. In group A, patients underwent treating with Regular + NPH Insulin, and in group B, patients underwent treating with Novo-rapid + Levemir Insulin. Patient’s demographic and clinical information gathered by specified several times during the study and analysis performed by SPSS21. RESULTS: Despite significant changes in the two groups patient’s blood glucose levels; we could not find any remarkable differences between the two groups. In the case of patient and health care system satisfaction and the length of the hospitalization group, B was better than group A. CONCLUSION: Altogether, The Novo-rapid and Levemir Insulin in comparing with the Regular and NPH Insulin were practically advantageous due to the simple using method and short hospitalization period of the patient. Thus, we prefer and suggest this beneficial method (using Novo-rapid and Levemir Insulin) to reach therapeutic goals.
Keywords: GDM, insulin regular, insulin novo-rapid, insulin NPH, insulin levemir
DOI: 10.3233/HAB-190385
Journal: Human Antibodies, vol. 27, no. 4, pp. 285-289, 2019
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