Affiliations: Anatomia Patológica, Hospitais da Universidade
de Coimbra, 3000 Coimbra, Portugal | Medicina Intensiva, Hospitais da Universidade de
Coimbra, 3000 Coimbra, Portugal | Medicina Intensiva, Hospitais da Universidade de
Coimbra, 3000 Coimbra, Portugal | Anatomia Patológica, Faculdade de Medicina e
Hospitais da Universidade de Coimbra, 3000 Coimbra, Portugal
Note: [] Address for Correspondence : Lina Carvalho Serviço de
Anatomia Patológica Hospitais da Universidade de Coimbra 3000 Coimbra,
Portugal FAX : 239835451
Abstract: The antiphospholipid syndrome can occur as a primary disease without
relationship to other immunologic complications and venous thrombosis following
assymptomatic thrombocytopenia comprehends the commom clinical course.
Circulating antibodies against cellular membranes phospholipids induce arterial
and venous trombosis in any organ as well as inflammatory reactions. In the
lung, embolism and alveolar hemorrhage are the expected complications. In
addition, interstitial lung disease may happen as in this case of a 23-year-old
woman with an abrupt onset of diffuse alveolar damage with bronchocentric
BOOP-like pattern confirmed by surgical lung biopsy; Budd-Chiari syndrome
joined perfusion renal failure and the acute respiratory syndrome; acute
cholecystitis developed five months after mechanical ventilation which lasted
for eight months.
