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Primary Choriocarcinoma of the lung

Article type: Other

Authors: Kayser, Klaus | Kayser, Gian | Kröger, Heiner | Herb, Karl-Peter | Tüngerthal, Sigfried

Affiliations: Department of Pathology, Department of Pulmonology, and Department of Pathology, Department of Pulmonology, and Department of Radiology, Thoraxklinik, D-69121 Heidelberg

Keywords: Choriocarcinoma, lung, brain metastases

Journal: Electronic Journal of Pathology and Histology, vol. 7, no. 2, pp. 09-09, 2001

Received 1 June 2001
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Accepted 1 June 2001
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Published: 2001
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Abstract

A fatal case with a primary choriocarcinoma of the lung is presented. The 43 year old women developed pain of the left chest wall for two months. Chest radiographs displayed a small peripherally localized tumor in the left upper lobe measuring 1 cm * 2 cm involving the adjacent pleura. She has been a smoker with about 20 pack years. The histology revealed an undifferentiated carcinoma; the immunohistology tumor cells with strong staining against ß-HCG and (weakly) against alpha-fetoprotein. The diagnosis of a primary choriocarcinoma of the lung was stated. The patient died after twenty-one months due to generalized tumor spread including brain metastases.