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A Rare Case of Stromal Sarcoma of the Endometrium with Sex-Cord-Like Differentiation

Article type: Other

Authors: Dietel, Manfred

Affiliations: Institute of Pathology, Charité, Humboldt University Berlin, Schumannstr. 20-21, 10117 Berlin e-mail: manfred.dietel@charite.de Tel.: ++49 30 450 536 002

Keywords: uterus, endometrial stromal sarcoma, sex-cord-like elements, glandular elements

Journal: Electronic Journal of Pathology and Histology, vol. 7, no. 2, pp. 08-08, 2001

Received 1 June 2001
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Accepted 1 June 2001
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Published: 2001
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Abstract

A grey firm uterine tumor of 8 cm in diameter was detected in a 35 y old patient. Histology revealed a biphasic growth pattern with glandular or epitheloid and sex-cord-like elements as well as a spindle cell component. The spindle cells resemble to a certain degree stromal cells of the endometrium. More than 10 mitoses/HPF were counted. IH disclosed a strong expression of vimentin and only focal positivity for CD99 and smooth muscle actin, no cytokeratin. In summary, the diagnosis of a rare case of a high-grade endometrial stromal sarcoma with sex-cord-like differentiation was stated.