Affiliations: Laboratory of Developmental Neurobiology, Department
of Surgery, Medicine & Lombardi Cancer Center, Georgetown University,
Washington, DC 20007, USA | Department of Veterans Affairs, Washington, DC 20049,
USA
Note: [] Corresponding author: B. Mishra and L. Mishra, Laboratory of
Developmental Biology/Digestive Diseases, Georgetown University, Medical/Dental
Building, NW 212, 3900 Reservoir Road, N.W., Washington, DC 20007, USA. E-mail:
bm72@georgetown.edu; lm229@georgetown.edu
Abstract: Transforming growth factor beta (TGF-β) signaling has diverse
and complex roles in various biological phenomena such as cell growth,
differentiation, embryogenesis and morphogenesis. ES cells provide an essential
model for understanding the role of TGF-β signaling in lineage
specification and differentiation. Recent studies have suggested significant
role of TGF-β in stem/progenitor cell biology. Here in this review, we
focus on the role of the TGF-β superfamily in neuronal development.
Journal: Disease Markers, vol. 24, no. 4-5, pp. 251-255, 2008
