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Issue title: BIOMARKERS IN OVARIAN DISEASE
Article type: Research Article
Authors: Wong, Kwong-Kwok | Gershenson, David
Affiliations: Department of Gynecologic Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, TX, USA
Note: [] Corresponding author: Kwong-Kwok Wong, Ph.D., Department of Gynecologic Oncology, Unit 1362, The University of Texas M. D. Anderson Cancer Center, P.O. Box 301439, Houston, TX 77230-1439, USA. Tel.: +1 713 713 792 0229; Fax: +1 713 745 5099; E-mail: kkwong@mdanderson.org
Abstract: The role of serous tumors of low malignant potential (LMP) in the development of invasive epithelial cancer of the ovary is debatable. This review summarizes the current clinical, genetic, and genomic evidence for the existence of a continuum comprising both LMP serous tumors and low-grade serous ovarian carcinomas.
Keywords: K-Ras, B-Raf, Ki-67, p53, low malignant potential, low-grade serous ovarian carcinoma, genomics
Journal: Disease Markers, vol. 23, no. 5-6, pp. 377-387, 2007
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