Affiliations: Riverside Research Institute, Biomedical Engineering
Laboratories, 156 William Street, New York, NY 10038-2609, USA | Case Western Reserve University, Department of
Biomedical Engineering, 10900 Euclid Avenue, Cleveland, Ohio 44106-7220,
USA
Note: [] Corresponding author: Ernest J. Feleppa, Ph.D., Biomedical
Engineering Laboratories, Riverside Research Institute, 156 William Street, New
York, NY 10038-2609, USA. Tel: +1 212 502 1775; Fax: +1 212 502 1729; E-mail:
feleppa@rrinyc.org
Abstract: Ultrasound has been a popular clinical imaging modality for decades.
It is well established as a means of displaying the macroscopic anatomy of
soft-tissue structures. While conventional ultrasound methodologies (i.e.,
B-mode and Doppler methods) are well proven and continue to advance technically
on a daily basis, e.g. by extending into higher frequencies and taking
advantage of harmonic phenomena in tissues, fundamentally new ultrasound
technologies also are emerging and offer exciting promise for making
significant improvements in the clinical imaging of disease. These emerging
methods include spectrum analysis, elasticity imaging, contrast-agent methods,
and advanced flow detection and measurement techniques. Each provides
independent information and, used alone, each can provide powerful new imaging
capabilities; combined with each other, their capabilities may be even greater
in many applications; and all in principle can be used in concert with other
imaging modalities to offer the possibility of further improvements in disease
detection, evaluation, and monitoring.
Journal: Disease Markers, vol. 18, no. 5-6, pp. 249-268, 2002
