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Article type: Research Article
Authors: Kässer, U.a | Heimburg, P.a | Walitza, E.b
Affiliations: [a] Robert Bosch Hospital, Dept. of Cardiology, Auerbachstr. 110, 7000 Stuttgart 50, FRG | [b] Fraunhofer IGB, Nobelstr. 12, 7000 Stuttgart 80, FRG
Note: [] Accepted by: Guest Editor I. Anadere (Received in final form by Executive Editorial Office 10.2.1989)
Abstract: With the aid of multiple linear regression analysis, the depedence of whole blood viscoelasticity on different laboratory parameters was investigated. Viscoelasticity was determined by means of an oscillating capillary rheometer at a frequency of 2 Hz and an amplitude of wall shear rate of 10 l/s. The results showed, that the viscous component of viscoelasticity depends mainly on hematocrit and to a small degree on plasma viscosity. The elastic component of viscoelasticity on the other hand is influenced to a greater extent by plasma viscosity and is additionally influenced by the plasma proteins (fibrinogen, albumin, and cholesterol) and platelets. Thus, 81% of the variation found for the viscous and 75% for the elastic component of a reference population of normal donors could be explained.
Keywords: Blood viscoelasticity, oscillatory capillary rheometry, normal values, laboratory parameters, multiple linear regression
DOI: 10.3233/CH-1989-9212
Journal: Clinical Hemorheology and Microcirculation, vol. 9, no. 2, pp. 307-312, 1989
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