Red cell phospholipids and membrane microviscosity in diabetics

Issue title: Memorial Issue for Robin Fåhraeus (1888–1968)

Article type: Research Article

Authors: Caimi, Gregorio^a | Catania, Anna^a | D’Asaro, Salvatrice^a | Serra, Antonio^a | Catalano, Concetta^a | Bono, Antonino^b | Sarno, Antonio^a

Affiliations: [a] Istituto di Clinica Medica e Malattie Cardiovascolari, Universitá di Palermo, Via del Vespro 129, 90127, Palermo, Italy | [b] Istituto di Chimica Biologica, Universitá di Palermo, Via del Vespro 129, 90127, Palermo, Italy

Note: [] Accepted by: Editor T. Di Perri

Abstract: We evaluated red cell phospholipids and the relationships between these lipidic components and membrane microviscosity in a group of 12 diabetics of type 1, in a group of 16 diabetics of type 2 and in a group of 12 normal controls. From the obtained data, it is evident that no significant difference is present between normals and diabetics of type 1 regarding the individual phospholipids; between normals and diabetics of type 2 a significant difference regarding sphyngomyeline and phosphatidylcholine/sphyngomyeline ratio is evident. No statistical difference of the membrane microviscosity is present between normals and diabetics of type 1 and 2. In normals and in diabetics of type 1 and 2 no relationship is evident between membrane microviscosity and individual phospholipids.

Keywords: Diabetes mellitus, erythrocyte phospholipids, membrane microviscosity

DOI: 10.3233/CH-1988-8615

Journal: Clinical Hemorheology and Microcirculation, vol. 8, no. 6, pp. 939-944, 1988