Multiple sclerosis: Haemorheological pattern

Article type: Research Article

Authors: Caimi, Gregorio^a | Savettieri, Giovanni^b | Fierro, Brigida^b | Catania, Anna^a | Sarno, Antonio^a

Affiliations: [a] Istituto di Clinica Medica e Malattie Cardiovascolari, Università di Palermo, Via del Vespro 129, 90127, Palermo, Italy | [b] Istituto di Clinica Neurologica, Università di Palermo, Via del Vespro 129, 90127, Palermo, Italy

Note: [] Accepted by: Editor J.A. Dormandy

Abstract: In 21 untreated subjects with definite multiple sclerosis (MS) we evaluated whole-blood viscosity at high and low shear rates, plasma and serum viscosity, haematocrit, fibrinogen, fibrinogen/albumin ratio, MEA and whole-blood filterability. From the obtained data, it is evident that whole-blood viscosity at high shear rates is reduced in MS compared to controls;no difference is evident at low shear rates. Plasma and serum viscosity as well as the haematocrit are lower in MS. Increased are instead the fibrinogen, fibrinogen/albumin ratio and MEA. No difference is present for VBC.

Keywords: multiple sclerosis, haemorheological determinants

DOI: 10.3233/CH-1987-7505

Journal: Clinical Hemorheology and Microcirculation, vol. 7, no. 5, pp. 695-698, 1987