Plenary lecture

Issue title: The Fourth European Conference on Clinical Hemorheology. Part I. Siena, Italy, 20–22 June 1985

Subtitle: Relations between molecular rheology and red blood cell structure: Methods and clinical approaches

Guest editors: Alfred L. Copley, Tullio Di Perri and Sandro Forconi

Article type: Research Article

Authors: Stoltz, J.F. | Donner, M.

Affiliations: U.284 INSERM, Brabois, 54511 Vandoeuvre, Los Nancy Cedex, France

Abstract: The red blood cell membrane is a complex medium with rheological characteristics that are dependent on a large number of parameters. These properties are connected with interaction phenomena between the red blood cell components (cytoskeleton, membrane lipids, etc.) which, when understood, make it easier to perceive certain biological phenomena. Several investigation techniques are available for studying membrane rheological properties at the molecular level (molecular emission spectroscopy, ESR, NMR, etc.). Among the most widely applied methods, spectroscopic techniques have been the subject of a large number of studies, because they are easy to apply and are highly sensitive. After a brief reminder of theoretical and methodological aspects, the authors consider the clinical applications of these methods to the red blood cells.

Keywords: Red blood cell, Molecular rheology, Membrane fluidity, Electron spin resonance, Fluorescence polarization

DOI: 10.3233/CH-1985-5603

Journal: Clinical Hemorheology and Microcirculation, vol. 5, no. 6, pp. 813-848, 1985