Affiliations: [a] Aging Brain Research Centre, Institute of Gerontology, University of Perugia, Policlinico Monteluce, 06100 Perugia, Italy | [b] Haemorheological Unit, Institute of Gerontology, University of Perugia, Policlinico Monteluce, 06100 Perugia, Italy | [c] Institute of Gerontology, University of Perugia, Policlinico Monteluce, 06100 Perugia, Italy
Note: [] Accepted by: Editor L. Dintenfass. Received in Executive Editorial Office 15.7.1985.
Abstract: Forty elderly patients suffering from primary mental deterioration were assessed for haemorheological factors and intellectual capacity. They were then divided into four randomized groups and treated with one of the following 1) PLACEBO 2) “TRENTAL” 400 (pentoxifylline) 3) “MENTIUM” (2-dimethylaminoethanol) 4) “NORZETAM” (2-oxo-1 pyrrolidone acetamide). After three months of treatment the two parameters were re-evaluated and the results compared with the pre-therapy data to establish whether there is any correlation between haemorheological values and psychological test scores. The differences found would seem to warrant further investigations on the role of haemorheological factors in mental deterioration, as well as on the three drugs tested.
Keywords: Mental deterioration, haemorheological factors in elderly, psychometric tests in elderly
