Relationship between rheological and morphological changes in stored erythrocytes

Issue title: Fifth International Congress of Biorheology. Part VI. Baden-Baden, F.R. Germany, 20–24 August, 1983. Symposium on Role of Hemorheology in Blood Transfusion

Guest editors: J.F. Stoltz

Article type: Research Article

Authors: Berling, C.^a | Lacombe, C.^a | Lelievre, J.C.^a | Quemada, D.^a | Mellotee, D.^b | Allary, M.^b | Fabre, G.^b | Saint Blancard, J.^b | Daveloose, D.^c | Leterrier, F.^c

Affiliations: [a] Unité de Biorhéologie, associée au CNRS LA 343, Département de Biophysique, CHU Pitié-Salpêtrière, 91 bd de l’Hôpital 75634 Paris Cedex 13, France | [b] Centre de Transfusion Sanguine des Armées “Jean Julliard”, 92141 Clamart, France | [c] Division de Biophysique du Centre de Recherche du Service de Santé des Armées, 92141 Clamart, France

Note: [] Accepted by: Editor J.F. Stoltz

Abstract: Rheological and morphological measurements are performed on blood stored in liquid state as packed cells in CPD anticoagulant solution. Rheological data are obtained from viscometric measurements and processed by means of Quemada’s model of blood viscometry. Morphological data are obtained from electron microscopy and by cells counting. A relationship between a parameter of Quemada’s law and rate of functional cells is established and experimentaly confirmed. As a result we show that viscometry is able to give precise information on the quality of stored blood.

Keywords: blood storage, viscometry, microscopy, rheological model

DOI: 10.3233/CH-1985-5304

Journal: Clinical Hemorheology and Microcirculation, vol. 5, no. 3, pp. 207-215, 1985