Rheological consequences of fibrinolysis and of anticoagulation

Issue title: Proceedings of Fifth International Congress of Biorheology. Baden-Baden, F.R. Germany, 20–24 August 1983. Symposium on Hemorheological Disorders in Cardiovascular Diseases

Guest editors: Alfred L. Copley and Siegfried Witte

Article type: Research Article

Authors: Bruhn, H.D.

Affiliations: Department of Medicine, University of Kiel, Schittenhelmstrasse 12, 2300 Kiel, F.R.G.

Abstract: After intravenous application of streptokinase or urokinase fibrinogenolysis takes place with the result of a reduction in blood and plasma viscosity and with a significant decline in the velocity of red cell aggregate formation and shear resistance of red cell aggregates. In addition, a drop on apparent blood viscosity at all shear rates is found. Preliminary data concerning the influence of heparin and coumarin therapy on blood rheology have to be reproduced by other laboratories.

Keywords: streptokinase, urokinase, fibrinogenolysis, blood viscosity, heparin, coumarin

DOI: 10.3233/CH-1984-4105

Journal: Clinical Hemorheology and Microcirculation, vol. 4, no. 1, pp. 29-34, 1984