Affiliations: [a]
Fraunhofer Institute for Applied Polymer Research (IAP), Department of Biomaterials, Healthcare and Cosmeceuticals, Potsdam-Golm, Germany
| [b] Institute of Biotechnology, Molecular Cell Biology, Brandenburg University of Technology, Senftenberg, Germany
Correspondence:
[*]
Corresponding author: A. Krüger-Genge, Fraunhofer Institute for Applied Polymer Research (IAP), Potsdam-Golm, Germany. E-mail: anne.krueger-genge@iap.fraunhofer.de.
Abstract: Arthrospira platensis (AP) and some of its derived products have well-established biological activities as antioxidants or as agents to reduce cardiovascular disease risk factors. Furthermore, AP products have gained increasing importance as potential anti-cancer agents. However, the ingredients of the available products vary greatly with the origin, the type of production and processing, which could have significant consequences for their biological effects. Therefore, the composition and biological influence of five distinct AP powders, which were acquired commercially or produced at a public biotechnology institute, were investigated in regard to their endothelialization capacity using a cell impedance- (CI) based measurement method. The study revealed that the AP composition and especially the influence on HUVEC proliferation differed significantly between the five AP powders up to 109%. Thus, it could be shown that the method used allows the reliable detection of quantitative differences in biological effects of different AP preparations.
