Affiliations: Department of Cardiology, The 8th Medical Center, Chinese PLA General Hospital, Bejing, China
Correspondence:
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Corresponding authors: Ning Hua, Department of Cardiology, The 8th Medical Center, Chinese PLA General Hospital, Bejing, China. Tel.: +86 010 55473053; E-mail: huaning309@163.com; ORCID: 0000-0001-8419-0830. Fakuan Tang, Department of Cardiology, The 8th Medical Center, Chinese PLA General Hospital, Bejing, China. E-mail: tfk616@sina.com.
Note: [1] These authors contributed equally to this work.
Abstract: BACKGROUD:Patients with chest pain and suspected of coronary artery disease(CAD) need further test to confirm the diagnosis. Magnetocardiography (MCG) is a non-invasive and emission-free technology which can detect and measure the weak magnetic fields created by the electrical activity of the heart. OBJECTIVE:This study aimed to investigate the usefulness of the 10 MCG parameters to detect CAD in patients with chest pain by means of a machine learning method of multilayer perceptron(MLP) neural network. METHODS:209 patients who were suffering from chest pain and suspected of CAD were enrolled in this cross-sectional study. In all patients, 12-lead electrocardiography(ECG) and MCG test were performed before percutaneous coronary angiography(PCA). 10 MCG parameters were analyzed by MLP neural networks. RESULTS:11 diagnostic models(M1 to M11) were established after MLP analysis. The accuracies ranged from 71.2% to 90.5%. Two models(M10 and M11) were further analyzed. The accuracy, sensitivity, specificity, PPV, NPV, PLR and NLR were 89.5%, 89.8%, 88.9%, 92.7%, 84.7%, 11.10 and 0.11, of M10, and were 90.0%, 91.4%, 87.7%, 92.1%, 86.6%, 7.43 and 0.10, of M11. CONCLUSIONS:By a method of MLP neural network, MCG is applicable in identifying CAD in patients with chest pain, which seems beneficial for detection of CAD.
