Contrast-enhanced ultrasound (CEUS) prediction of focal liver lesions in patients after liver transplantation in comparison to histopathology results

Issue title: Developments in the application of high resolution ultrasound in clinical diagnostics

Article type: Research Article

Authors: Rübenthaler, J.^{; *} | Paprottka, K.J. | Hameister, E. | Hoffmann, K. | Joiko, N. | Reiser, M. | Rjosk-Dendorfer, R.^{; 1} | Clevert, D.A.^{; 1}

Affiliations: Department of Clinical Radiology, Ludwig-Maximilians-University of Munich-Grosshadern Campus, Munich, Germany

Correspondence: [*] Corresponding author: Dr. med. Johannes Rübenthaler, Department of Clinical Radiology, Interdisciplinary Ultrasound Center, University of Munich – Grosshadern Campus, Marchioninistr. 15, Munich 81377, Germany. Tel.: +49 89 44007 3627; Fax: +49 89 44007 8832; E-mail: Johannes.Ruebenthaler@med.uni-muenchen.de.

Note: [1] These authors contributed equally to the study.

Abstract: PURPOSE: To investigate the value of contrast-enhanced ultrasound (CEUS) in histologic prediction of focal liver lesions after liver transplantation. MATERIALS AND METHODS: 10 focal liver lesions in 10 patients after liver transplantation were scanned using CEUS and the CEUS results were compared with the histopathological results. RESULTS: Among 10 focal liver lesions, 7 proofed to be histopathological benign and 3 lesions proofed to be histopathological malignant. All lesions (100%) were correctly report as benign or malignant in the report of the CEUS examination. CONCLUSION: CEUS can be helpful in the differentiation of benign and malignant focal liver lesions in patients after liver transplantation and can be used in clinical management of focal liver lesions.

Keywords: CEUS, (Contrast-enhanced, ultrasound), histopathology, liver transplantation, focal liver lesions

DOI: 10.3233/CH-179104

Journal: Clinical Hemorheology and Microcirculation, vol. 66, no. 4, pp. 303-310, 2017