Elasticity and fracture strain of whole blood clots

Article type: Research Article

Authors: Riha, P.^; | Wang, X. | Liao, R. | Stoltz, J.F.

Affiliations: Institute of Hydrodynamics, Academy of Sciences, 166 12 Prague, Czech Republic | Department of Pharmacology, Institute of Chinese Materia Medica, Beijing, 100700, China | Angiohematology–Hemorheology, Faculty of Medicine, 54500 Vandoeuvre les Nancy, France

Note: [] Address for correspondence: Dr P. Riha, Institute of Hydrodynamics, Academy of Sciences of the Czech Republic, Pod Patankou 5, 166 12 Prague, Czech Republic. Fax: +420 2 32 21 81; E‐mail: riha@ ih.cas.cz.

Abstract: The measurement of clot elasticity and fracture strain is carried out using a rotational rheometer with a controlled stress system. The elasticity is quantified by a shear elastic modulus and fracture strain by a critical strain (deformation) when the clot begins to break up. The results indicate a decrease of elasticity and increase of fracture strain of the clot with increasing hematocrit. Moreover, the elastic modulus of the clot is not constant but increasing with deformation.

Journal: Clinical Hemorheology and Microcirculation, vol. 21, no. 1, pp. 45-49, 1999