The differential enhancement pattern of contrast enhanced ultrasound and magnetic resonance imaging characteristics in hepatic angiomyolipoma: 7 case reports

Article type: Research Article

Authors: Kong, Wen-Tao^a | Tang, Min^b | Qiu, Yu-Dong^{c; *} | Shi, Jiong^d | Wu, Min^{a; *}

Affiliations: [a] Department of Ultrasound, Drumtower Hospital Affiliated to Medicial College of Nanjing University, Nanjing, China | [b] Department of Radiology, Drumtower Hospital Affiliated to Medicial College of Nanjing University, Nanjing, China | [c] Department of Hepatobiliary Surgery, Drumtower Hospital Affiliated to Medicial College of Nanjing University, Nanjing, China | [d] Department of Pathology, Drumtower Hospital Affiliated to Medicial College of Nanjing University, Nanjing, China

Correspondence: [*] Corresponding authors: Min Wu, Department of Ultrasound, Drumtower Hospital Affiliated to Medicial College of Nanjing University, Nanjing, China. Tel.: +86 25 83304616; E-mail: wuminguyi@163.com and Yu-Dong Qiu, Department of Hepatobiliary Surgery, Drumtower Hospital Affiliated to Medicial College of Nanjing University, Nanjing, China. Tel.: +86 25 83304616; E-mail: yudongqiu510@163.com.

Abstract: OBJECTIVE:To compare the enhancement pattern of hepatic angiomyolipoma (HAML) on contrast enhanced ultrasound (CEUS) and magnetic resonance (MR). METHODS:The data of seven patients (females; age 28–52 years; mean, 42 years) with histologically proven HAMLs were retrospectively reviewed. All patients underwent CEUS and MR examination. The images were analyzed by two experienced doctors who blinded to the clinical and pathological information of cases. RESULTS:The mean diameter of the nodule was 5.7 cm (range: 3.2–10 cm). Histopathologic results revealed 4 nodules to be myomatous type and 3 nodules to be mixed type. All nodules showed hyperenhanced during arterial phase on both CEUS and MRI. During portal and delayed phase, washout was more showed on MRI (5/7, 71.4%) than on CEUS (2/7, 28.6%). CONCLUSIONS:There is discrepancy of enhancement pattern between CEUS and MRI. The quick wash-in and sustained hyperenhancement on CEUS may be helpful for the diagnosis of HAML.

Keywords: Hepatic angiomyolipoma, contrast enhanced ultrasound, magnetic resonance imaging, enhancement pattern

DOI: 10.3233/CH-170317

Journal: Clinical Hemorheology and Microcirculation, vol. 71, no. 1, pp. 17-26, 2019