Issue title: Selected articles of the 14th International Congress of Biorheology and the 7th International Conference of Clinical Hemorheology, July 4–7, 2012, Istanbul, Turkey
Article type: Research Article
Authors: Tripette, Julien | Hardy-Dessources, Marie-Dominique; ; | Romana, Marc; ; | Hue, Olivier | Diaw, Mor | Samb, Abdoulaye | Diop, Saliou | Connes, Philippe; ; ;
Affiliations: Department of Exercise Physiology, National Institute of Health and Nutrition, Shinjuku, Tokyo, Japan | Inserm UMR 665, Hôpital Ricou, CHU de Pointe-à-Pitre, Pointe-à-Pitre, Guadeloupe | Université des Antilles et de la Guyane, Pointe-à-Pitre, Guadeloupe | Laboratory of Excellence GR-Ex «The red cell: from genesis to death», PRES Sorbonne Paris Cité, Paris, France | Laboratoire ACTES EA3596, Département de Physiologie, Université des Antilles et de la Guyane, Pointe-à-Pitre, Guadeloupe | Laboratoire de Physiologie et Explorations fonctionnelles, FMPOS, UCAD, Dakar, Senegal | Laboratoire d'hémato-immunologie, FMPOS, UCAD, Dakar, Senegal
Note: [] Corresponding author: Philippe Connes, Inserm UMR 665, Hôpital Ricou, CHU de Pointe-à-Pitre, 97157 Pointe-à-Pitre, Guadeloupe. E-mail: pconnes@yahoo.fr
Abstract: This review presents the epidemiological data regarding the exercise-related complication in exercising sickle cell trait carriers, and focuses on the different potential mechanisms that could be involved in these adverse events, such as hemorheological alterations, inflammation, vascular adhesion of circulating blood cells, oxidative stress and impaired nitric oxide metabolism. We also discuss the effects of different modulating factors such as vascular function, environment (hot temperature), hydration status, physical fitness, exercise intensity and genetic factors.
Keywords: Sickle cell trait, exercise-related sudden death, hemorheology, inflammation, vascular function
DOI: 10.3233/CH-131687
Journal: Clinical Hemorheology and Microcirculation, vol. 55, no. 1, pp. 29-37, 2013
