Affiliations: Dipartimento Biomedico di Medicina Interna eSpecialistica, Università di Palermo, Italy
Correspondence:
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Corresponding author: Prof. Gregorio Caimi, Dipartimento Biomedico di Medicina Interna e Specialistica, Università degli Studi di Palermo, Via del vespro 129, Palermo 90100, Italy. Tel.: +39 091 6554406; Fax: +39 091 6554535; E-mail: gregorio.caimi@unipa.it.
Abstract: In this brief review, we have examined some clinical conditions that result to be associated to an altered hemorheological profile and at times accompanied by skin ulcers. This skin condition may be observed in patients with the following condtions, such as primary polycythemic hyperviscosity (polycythemia, thrombocytemia) treated with hydroxyurea, primary plasma hyperviscosity (multiple myeloma, cryoglobulinemia, cryofibrinogenemia, dysfibrinogenemia, and connective tissue diseases), primary sclerocythemic hyperviscosity (hereditary spherocytosis, thalassemia, and sickle cell disease). In addition, it may be present in patients with secondary hyperviscosity conditions such as diabetes mellitus, arterial hypertension, critical limb ischemia and chronic venous insufficiency.
