Haemorheological changes in the patients of myocardial infarction and stroke

Article type: Research Article

Authors: Dhar, Promila | Seshadri, V. | Jayaraman, G.

Affiliations: Biomechanics Division, Centre for Atmospheric Sciences, Indian Institute of Technology, New Delhi - 110016 | Department of Applied Mechanics, Indian Institute of Technology, New Delhi - 110016

Abstract: Blood viscosity and yield stress of patients with myocardial infraction and stroke were studied and the observations were cotnpared with those of people who served as control. Viscosity at various shear rates was measured using Weissenberg rheogoniometer equipped with simple cone and plate type of platens. Blood, being a Non-Newtonian fluid, Casson model was used to describe its behaviour adequately. The changes in the independent rheological properties (viscosity and yield stress) of whole blood, packed RBC and plasma were studied. Viscosities of whole blood as well as packed RBC were observed to increase significantly in patients with myocardial infarction, and stroke. Plasma viscosity also registered increase in myocardial infarction patients, while increase in stroke patients was insignificant. Significant increase iit the yield stress of whole blood in patients with myocardial infarction was observed, but there was no significant change in the yield stress of packed RBC in either category of patients

Keywords: Viscosity, yield stress, Haemorheology, Weissenberg rheogoniometer, myocardial infarction, stroke

DOI: 10.3233/CH-1995-15503

Journal: Clinical Hemorheology and Microcirculation, vol. 15, no. 5, pp. 715-727, 1995