Erythrocyte as a link between basic and clinical research

Issue title: Selected Proceedings of the 16th Conference of the European Society for Clinical Hemorheology and Microcirculation (ESCHM), 18–21 June, 2011, Munich, Germany

Article type: Research Article

Authors: Saldanha, C.^; | de Almeida, J.P. Lopes^;

Affiliations: University of Lisbon Medical School, Santa Maria Hospital, Lisbon, Portugal | Institute of Biochemistry, Institute of Molecular Medicine, Faculty of Medicine, University of Lisbon, Lisbon, Portugal

Note: [] Corresponding author: J.P. Lopes de Almeida, Institute of Biochemistry, Institute of Molecular Medicine, Faculty of Medicine, University of Lisbon, Av. Prof. Egas Moniz, 1649-028 Lisbon, Portugal. E-mail: carlotasaldanha@fm.ul.pt

Abstract: We review the major hemorheological experimental studies that show the erythrocyte aggregation as a link between basic and clinical research. The results of the clinical cross-sectional and longitudinal studies presented here will highlight the possible association between erythrocyte aggregation and plasma fibrinogen. Basic studies conducted in vitro are also mentioned as for its relevance in answering questions raised in clinical settings, as well as and in understanding the underlying influent factors in the erythrocyte tendency to aggregate and disaggregate.

DOI: 10.3233/CH-2011-1496

Journal: Clinical Hemorheology and Microcirculation, vol. 49, no. 1-4, pp. 463-472, 2011