Affiliations: Dept. of Experimental Medicine, Paediatric Clinic, School of Medicine, University of L'Aquila, Collemaggio, 67100 L'Aquila - Italy | Dept. of Biomedical Sciences and Technology and Biometry, Laboratory of Human Physiology, School of Medicine, University of L'Aquila, Collemaggio, 67100 L'Aquila - Italy
Abstract: Hemorheological parameters were analyzed on 50 simple type obese children after 12 months of an adequate diet and physical training. According to the changes of body weight, the subjects were divided into three groups. The hyperviscosity condition disappeared in obese children with a real weight loss, while it remained in the groups of subjects with persistent overweight and with increased weight. A decrease of erythrocyte membrane lipid peroxidation, expressed as malondialdehyde (MDA) , was observed only in the children with a real weight loss, suggesting that the persistent trend toward lipid peroxidation may be considered a significant risk factor for atherosclerosis.
Keywords: atherosclerosis, obesity, hemorheological parameters, lipid peroxidation, weight loss
