Affiliations: Department of Neurology, Karl-Franzens University of Graz, Austria | Department of Neurology, School of Medicine, Poznan, Poland
Note: [] Piotr Kowal, M.D., Dept. of Neurology, School of Medicine, Przybyszewskiego 49, Poznan, Poland
Note: [] Manfred Walzl, M.D., Dept. of Neurology, Karl-Franzens University of Graz, Auenbruggerplatz 22, A-8036 Graz, Austria
Abstract: At a constant haematocrit ratio the yield shear stress (YSS) depends on the level of fibrinogen and on the influence of other plasma constituents, erythrocyte membrane changes on the red cells and fibrinogen interaction. The study of the influence of the H.E.L.P. system on the value of YSS was carried out in 9 patients with vascular disease (acute stroke - 3 patients -, multi-infarct dementia - 3 patients -, peripheral arteriosclerotic vascular disease - 2 patients - and coronary heart disease - 1 patient) in the model of diluted plasma media varying in fibrinogen concentration. The H.E.L.P. system application significantly decreased the value of YSS (p<0.001), which was related to the parallel reduction of the fibrinogen level (p<0.001) and plasma viscosity (p<0.001). The significant coefficients of correlations were found out between following parameters: YSS and fibrinogen (p<0.001), YSS and plasma viscosity (p<0.001) and fibrinogen and plasma viscosity (p<0.001) .
