Plasma viscosity dependence on proteins and lipoproteins

Subtitle: Results of the Aachen study

Article type: Research Article

Authors: Jung, F. | Pindur, G. | Kiesewetter, H.

Affiliations: Department of Clinical Haemostasiology and Transfusion Medicine, University of Saarland, 6650 Homburg/Saar, Germany

Abstract: In 2821 participants of the Aachen study plasma viscosity, fibrinogen, immunoglobulin-M, α2-macroglobulin, total cholesterol, HDL cholesterol and triglyceride concentration has been measured in order to evaluate the influence of proteins and lipoproteins on plasma viscosity. The influence of molecular concentration, resp. concentration of molecular complexes can be estimated in plasma viscosity by stepwise regression analysis. All selected factors determine and, thus, characterize plasma viscosity. Negative correlation has only been observed in HDL concentration, i.e., with increasing HDL cholesterol concentration plasma viscosity decreases. The biological and fluid dynamical cause for this rare phenomenon is discussed.

Keywords: Plasma viscosity, plasma lipids, plasma proteins, Aachen study

DOI: 10.3233/CH-1992-12409

Journal: Clinical Hemorheology and Microcirculation, vol. 12, no. 4, pp. 557-571, 1992