Magnetic resonance lymphography: A novel technique for lymph node assessment in gynecologic malignancies

Issue title: Nanoparticle enhanced imaging: Emerging oncologic applications

Guest editors: M.G. Harisinghani

Article type: Research Article

Authors: Narayanan, P.^{a; *} | Iyngkaran, T.^a | Sohaib, S.A.^b | Reznek, R.H.^a | Rockall, A.G.^a

Affiliations: [a] Department of Radiology, St Bartholomews Hospital, London, UK | [b] Department of Radiology, Royal Marsden Hospital, London, UK

Correspondence: [*] Corresponding author: Priya Narayanan, Academic Department of Radiology, Dominion House, 59 Bartholomew Close, London EC1A 7ED, UK. Tel.: +44 207 601 8864; Fax: +44 207 601 8868; E-mail: priya21@doctors.org.uk.

Abstract: Lymph node status determines both prognosis and treatment choice in gynecological malignancies. Both CT and MRI are standard techniques used to detect lymph node involvement but these techniques have low sensitivity and specificity. Magnetic resonance lymphography (MRL) using iron oxide nanoparticles is a new technique for lymph node assessment which has shown much promise. This article discusses the applications of MRL in the setting of gynecological malignancy.

Keywords: Magnetic resonance lymphography (MRL), nanoparticles, gynecologic imaging

DOI: 10.3233/CBM-2009-0543

Journal: Cancer Biomarkers, vol. 5, no. 2, pp. 81-88, 2009