Affiliations: [a] Department of Pharmaceutical Analysis, Faculty of Pharmacy, Fujian Medical University, Fuzhou 350108, Fujian, China | [b] Department of Pharmacy, Pharmacy and Medical Technology School, Putian University, Putian 351100, Fujian, China | [c] Department of Clinical Laboratory, First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, Fujian, China | [d] Department of Pathology, First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, Fujian, China
Correspondence:
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Corresponding author: Qicai Liu, Department of Laboratory Medicine, First Affiliated Hospital of Fujian Medical University, 20 Chazhong Road, Taijiang District, Fuzhou 350005, Fujian, China. Tel.: +86 591 87981972; Fax: +86 591 2263520; E-mail: lqc673673673@163.com.
Note: [1] The two authors contributed equally to this work.
Abstract: Pancreatic cancers with poor prognosis are highly malignant, readily metastatic and of immune tolerance, mainly due to delayed detection. The metastatic progression and immune tolerance of pancreatic cancer is greatly attributed to the intercellular communication. However, exosomes are deemed to be the most important tool of intercellular communicators. Thus, we present a review of pancreatic cancer and exosomes in this article. We intensively summarize the progress of early pancreatic cancer and the relationship of the proliferation, progression and metastasis of pancreatic cancer and pancreatic cancer-derived exosomes, and propose new ideas of the study of pancreatic cancer.
