MicroRNA in non-melanoma skin cancer

Issue title: MiRNAs in Cancer: Non-coding RNAs as Appealing Biomarkers for Malignancy

Guest editors: Pier Jr Morin

Article type: Research Article

Authors: Sand, Michael^{a; *} | Sand, Daniel^b | Altmeyer, Peter^a | Bechara, Falk G.^a

Affiliations: [a] Department of Dermatology, Venereology and Allergology, Ruhr-University Bochum, Bochum, Germany | [b] Department of Medicine, Olive View UCLA Medical Center, University of California, Los Angeles, CA, USA | Department of Chemistry and Biochemistry, Université de Moncton, 18 Antonine-Maillet Avenue, Moncton, New Brunswick, Canada E1A 3E9

Correspondence: [*] Address for correspondence: Michael Sand, M.D., Dermatologic Surgery Unit, Department of Dermatology, Venereology and Allergology, Ruhr-University Bochum, St. Josef Hospital, Gudrunstr. 56, 44791 Bochum, Germany. Tel.: +49 234 5090; Fax: +49 234 5093445; E-mail: michael.sand@ruhr-uni-bochum.de.

Abstract: MicroRNAs (miRNAs) are a fairly novel class of 17- to 23-nucleotide (nt), short, non-coding RNA molecules that have revolutionized our understanding of gene regulation and opened new possibilities in the future of gene therapy. Here, we review the potential role of miRNAs in non-melanoma skin cancer (NMSC) and summarize the current studies available in this new aspect of NMSC research.

Keywords: microRNA, non-melanoma skin cancer, epithelial skin cancer, basal cell carcinoma, cutaneous squamous cell carcinoma

DOI: 10.3233/CBM-2012-0274

Journal: Cancer Biomarkers, vol. 11, no. 6, pp. 253-257, 2012