Affiliations: Department of Radiology and Radiological Science, Johns Hopkins Medical Institute, Baltimore, MD, USA
Correspondence:
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Corresponding author: Bonmyong Lee, Department of Radiology and Radiological Science, Johns Hopkins Medical Institute, 1800 Orleans St. Baltimore, MD 21287, USA. Tel.: +1 410 955 5000; E-mail:blee111@jhmi.edu
Abstract: A 49 year-old female underwent breast MRI for further evaluation of a single
projection mammographic finding. MR showed normal breast tissue; however, a
3 cm right lung mass was incidentally discovered, and later confirmed by
chest CT. Four years after upper lobectomy, lymphadenectomy, and
chemoradiation for stage IIIA non-small cell lung cancer, she presented with
a breast rash. Punch biopsy of the breast rash showed metastatic
adenocarcinoma consistent with lung primary. One year later, diffuse
bilateral breast edema and pleomorphic calcifications were present on
mammogram. Pathology revealed multifocal intralymphatic adenocarcinoma,
consistent with metastasis from lung primary. This unusual case illustrates
an incidentally discovered lung carcinoma found on breast MR that, over
time, spread to the breast via the lymphatic system.
