Affiliations: [a] Department of Surgery, Jeroen Bosch Hospital, ’s-Hertogenbosch, The Netherlands | [b] Department of Pathology, Jeroen Bosch Hospital, ’s-Hertogenbosch, The Netherlands
Correspondence:
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Corresponding author: I.M. Brouwer de Koning, Department of Surgery, Jeroen Bosch Hospital, Henri Dunantstraat 1, 5223 GZ ’s-Hertogenbosch, The Netherlands. Tel.: +31 73 553 3640; E-mail: i.brouwerdekoning@jbz.nl
Abstract: BACKGROUND:Fibroadenomas are the most common benign breast lesions in women. They present as a unilateral mass and can rapidly enlarge in size through hormonal changes. Fibroadenomas could be classified as small or giant, and as simple or complex. They are classified as ‘giant’ when the size exceeds 5 cm and/or weight 500 gram; and as ‘complex’ if one of the following characteristics is present: cysts with a size >3 mm, epithelial calcifications, sclerosing adenosis and papillary apocrine metaplasia. Giant fibroadenomas can cause compression of surrounding breast tissue or breast asymmetry, requiring surgical excision in order to preserve a normal breast shape. CASE:A 26-year-old pregnant woman was referred with a palpable mass of her right breast. The mass rapidly increased in size to a diameter of 13 cm during the second trimester of her pregnancy. A tru-cut biopsy confirmed a fibroadenoma. The rapid growth and compression of normal breast tissues indicated a lumpectomy during her pregnancy. The mass was easily excised without any consequences for the pregnancy. Pathological examination showed a complex giant fibroadenoma. CONCLUSION:A unique case of a pregnant woman with rapid progression of a fibroadenoma that met the criteria of a complex and giant fibroadenoma, was presented. This case emphasizes the importance of timely surgical intervention, even during pregnancy, to prevent permanent breast tissue damage.
