Low diffusion level within a fibroadenoma as the sole sign of ductal carcinoma in situ: A case report

Article type: Case Report

Authors: Tagliati, Corrado^a; | Lanni, Giuseppe^a | Cerimele, Federico^b | Di Martino, Antonietta^a | Calamita, Valentina^a | Lucidi Pressanti, Gabriella^a | Mingliang, Ying^c | Giuseppetti, Gian Marco^b | Argalia, Giulio^b | Giovagnoni, Andrea^b

Affiliations: [a] U.O.S.D. Radiologia Ospedale “San Liberatore” Atri, Dipartimento dei Servizi, ASL Teramo, Teramo, Italy | [b] Department of Radiological Sciences, Azienda Ospedaliero Universitaria Ospedali Riuniti, Università Politecnica delle Marche, Ancona, Italy | [c] Department of Radiology, Jinhua Municipal Central Hospital, Jinhua, Zhejiang, China

Correspondence: [*] Corresponding author: Corrado Tagliati, U.O.S.D. Radiologia Ospedale “San Liberatore” Atri - Dipartimento dei Servizi - ASL Teramo, Viale del Risorgimento, 1158, 64032 Atri, Teramo, Italy. Tel.: +39 366 2677166/+39 085 8707567; Fax: +39 085 8707308; E-mail: corrado.tagliati@gmail.com, corrado.tagliati@aslteramo.it. ORCIDs: http://orcid.org/0000-0002-4630-1090 (C. Tagliati);http://orcid.org/0000-0003-2535-4043 (Y. Mingliang)

Abstract: We present a case of ductal carcinoma in situ within a fibroadenoma. Breast cancer arising within fibroadenoma incidence ranges from 0.125% to 0.02%, and ductal carcinoma in situ is not the most frequent malignancy that can be found within a fibroadenoma. Dynamic contrast-enhanced magnetic resonance imaging showed an oval mass with circumscribed margins and dark internal septations, suspicious for fibroadenoma. According to European Society of Breast Radiology diffusion-weighted imaging consensus, mean apparent diffusion coefficient value obtained by drawing a small region of interest on the lesion apparent diffusion coefficient map showed a low diffusion level. Therefore, ductal carcinoma in situ within a fibroadenoma was diagnosed at final pathology after surgical excision.

Keywords: Breast cancer, fibroadenoma, ductal carcinoma in situ, ADC

DOI: 10.3233/BD-201080

Journal: Breast Disease, vol. 40, no. 4, pp. 283-286, 2021