Invasive ductal carcinoma mammographic findings: Correlation with age, breast composition and tumor size

Article type: Research Article

Authors: Cerimele, Federico^a | Tagliati, Corrado^b; | Salvatori, Fabio^a | Baldassarre, Silvia^a | Di Martino, Antonietta^b | Calamita, Valentina^b | Pressanti, Gabriella Lucidi^b | Mingliang, Ying^c | Giuseppetti, Gian Marco^a | Giovagnoni, Andrea^a

Affiliations: [a] Department of Radiological Sciences, Azienda Ospedaliero Universitaria Ospedali Riuniti, Università Politecnica delle Marche, Ancona, Italy | [b] Radiologia, ASL 4 Teramo, Italy | [c] Department of Radiology, Jinhua Municipal Central Hospital, Jinhua, Zhejiang, China

Correspondence: [*] Corresponding author: Corrado Tagliati, Radiologia, Azienda Sanitaria Locale 4 Teramo, Piazza Italia, 64100 Teramo, Italy. Tel.: +39 366 2677166/+39 085 8707567; Fax: +39 085 8707308; E-mails: corrado.tagliati@gmail.com, corrado.tagliati@aslteramo.it. ORCIDs: https://orcid.org/0000-0002-4630-1090 (C. Tagliati);https://orcid.org/0000-0003-2535-4043 (Y. Mingliang)

Abstract: BACKGROUND/OBJECTIVE:The aim of this study was to identify the mammographic findings associated with malignancy in different age groups, taking into account breast composition (BC) and lesion size. METHODS:Preoperative mammograms of 1023 invasive ductal carcinomas were retrospectively evaluated. According to the American College of Radiology Breast Imaging Reporting and Data System, cancer mammographic findings were classified as mass, calcifications, architectural distortion and asymmetry, and breasts were assessed as non-dense (A or B BC) and dense (C or D BC). Patient cohort was subdivided into three age groups (group 1: <50 years of age; group 2: between 50 and 69; group 3: ≥70 years of age). RESULTS:Significant results of multinomial logistic regression were the association between mass and non-dense breast (p < 0.0001) and the association between mass and tumor size larger than 15 mm (p = 0.0049). CONCLUSIONS:Mass finding of invasive ductal breast carcinoma is associated with breast composition and tumor size.

Keywords: Breast cancer, mammographic findings, age groups, breast composition, tumor size

DOI: 10.3233/BD-201072

Journal: Breast Disease, vol. 41, no. 1, pp. 45-49, 2022