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Article type: Research Article
Authors: Robins Sadler, Georgiaa; * | Olson, Linda K.b | Krause, Alan S.c | Saloufakos, Angela J.c | Ko, Celine M.c | Kabban, Victoria A.c | Ghazikhanian, Jenia L.c | Harshburger, Ryan J.c | Anghel, Mihai C.c | Saltzstein, Sidney L.d
Affiliations: [a] Director for Community Outreach, UCSD Cancer Center and Associate Clinical Professor of Surgery, UCSD School of Medicine, USA | [b] UCSD Cancer Center and Professor of Clinical Radiology, UCSD School of Medicine, USA | [c] UCSD Cancer Center, USA | [d] UCSD Cancer Center and Professor of Clinical Oncology and Pathology and Adjunct Professor of Family and Preventive Medicine, UCSD School of Medicine, USA
Correspondence: [*] Corresponding author: Georgia Robins Sadler, MBA, PhD, Director for Community Outreach, UCSD Cancer Center 0658, 9500 Gilman Drive, La Jolla, California 92093-0658, USA. Tel.: +1 858 534 7611; Fax: +1 858 534 7628; E-mail: gsadler@ucsd.edu.
Abstract: Background:Despite the growing number of older people in the population, this age group continues to be under represented in clinical trials. As a result, physicians must base treatment decisions for older patients on data from studies involving primarily younger, and presumably healthier, adults. Little experience is available to guide the development of study methodologies that will enhance the recruitment of older patients to clinical studies. Methods:This pilot study compared two methods of recruiting women 75 years and older to a clinical research study related to their most recent screening mammogram. The effectiveness of a single, in-person invitation to participate made during the screening mammogram appointment was compared with the effectiveness of a single invitation to participate sent by-mail following a screening mammogram. Results:Both methods succeeded in recruiting a sizable sample (N = 2,394). The in-person invitation to participate was more labor-intense and less likely to be inclusive of all eligible women, but secured a significantly greater proportion of the women to participate. However, once recruited, women in the by-mail method were significantly more likely to comply with the optional elements of the study and to express a willingness to continue with follow-up studies than those recruited by the in-person method. Conclusions:Lack of participation of older women in clinical research may be more a reflection of not being asked, rather than their lack of willingness to participate, thus reinforcing the key role health care providers can play in recruiting older women to clinical studies.
Keywords: Clinical trials, elder, recruitment, neoplasms
DOI: 10.3233/BD-2001-13105
Journal: Breast Disease, vol. 13, no. 1, pp. 33-40, 2001
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