Affiliations: 101 Manning Drive, CB 7570, University of North Carolina, Chapel Hill, NC 27759, USA. Tel.: +1 919 966 5288; Fax: +1 919 966 5214; E-mail: ringland_murray@med.unc.edu | University of North Carolina, Chapel Hill, NC, USA
Abstract: Background:Breast cancer is the most common malignancy to affect women of reproductive age. As more women are delaying fertility into the 4th and 5th decade of life, more women face the possibility of a breast cancer diagnosis prior to accomplishing their reproductive goals. Methods:Literature review PubMed, EMBASE. Conclusions:From expectant management, hormonal suppression, in vitro fertilization with embryo freezing, to egg and ovarian tissue cryopreservation, numerous fertility sparing options are available to women with breast cancer. Therapy will be individualized based on a patient’s age, financial resources, availability of services, cancer prognosis, ER/PR receptor, HER2 and BRCA status.
Keywords: Breast cancer, premature ovarian failure, fertility preservation
DOI: 10.3233/BD-2006-23110
Journal: Breast Disease, vol. 23, no. 1, pp. 73-80, 2006
