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Article type: Research Article
Authors: Huyghe, Jacques M.a | Oomens, Cees W.b | van Campen, Dick H.b | Heethaar, Robert M.c
Affiliations: [a] Dept. of Biophysics, University of Limburg, Maastricht, The Netherlands | [b] Dept. of Mech. Eng., Eindhoven University of Technology, Eindhoven, The Netherlands | [c] Dept. of Biomed. Eng., Twente University, Enschede, The Netherlands
Note: [] Accepted by: Editor P. Gaehtgens
Abstract: A mixture theory has been used to formulate a theory of blood perfusion. By means of a formal averaging procedure the discrete network of microvessels is transformed into a continuum. During this procedure, the distinction between arterioles, capillaries and venules is preserved by means of an arteriovenous parameter. In this paper, two equations are derived for the case of low Reynolds number steady-state flow through a rigid vessel network: the extended Darcy equation and the continuity equation. A verification of the theory is presented, on the basis of a network analysis.
Keywords: porous media, mixture, regional blood flow, collateral flow, Darcy, averaging
DOI: 10.3233/BIR-1989-26105
Journal: Biorheology, vol. 26, no. 1, pp. 55-71, 1989
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