Dynamic evaluation of aggregation and agglutination of red blood cells

Issue title: New Methods in Biorheology. Proceedings of the International Symposium held in Nancy, France, 17–18 August 1983. A Satellite Symposium of the Fifth International Congress of Biorheology

Guest editors: J.F. Stoltz and E. Puchelle

Article type: Research Article

Authors: Kaibara, Makoto | Date, Munehiro | Fukada, Eiichi

Affiliations: The Institute of Physical and Chemical Research, Wako, Saitama 351, Japan

Abstract: Viscoelastic evaluation of aggregation and agglutination of red blood cells was attempted. A concentric double cylinder viscoelastometer was used for determining the dynamic rigidity modulus and loss modulus of blood sample. The dynamic rigidity modulus of horse blood were measured over a wide range of hematocrit. The relation between the viscoelastic behavior and the erythrocyte sedimentation was examined. The change in the amount of surface charge of enzyme treated red blood cells was qualitatively estimated from the measurements of dynamic viscoelasticity of red blood cells suspension with added poly-L-lysine. The dynamic rigidity modulus of red blood cells agglutinated by adding lectin (concanavalin A) were also measured.

Keywords: viscoelasticity, rouleau, erythrocyte sedimentation, concanavalin A

DOI: 10.3233/BIR-1984-23S107

Journal: Biorheology, vol. 23, no. s1, pp. 43-47, 1984