Affiliations: Advanced Computer Center, RIKEN, 2‐1Hiro‐sawa, Wako‐shi, 351‐0198, Japan | Department of Mechanical and Systems Engineering, Nagoya Institute of Technology, Japan | Indian Institute of Technology, Kanpur, India
Note: [] Address for correspondence: Dr. Ryutaro Himeno, Advanced Computer Center, RIKEN, 2‐1Hiro‐sawa, Wako‐shi, 351‐0198, Japan. Tel.: +81 48 467 9321; Fax: +81 48 463 4634; E‐mail: himeno@postman.riken.go.jp.
Abstract: The aim of this study is to examine the interaction between two mild atherosclerotic proliferations spaced apart by a distance S by analyzing their influence on flow structure, pressure drop and stress field in an arterial vessel under pulsatile flow conditions. This has been achieved numerically by employing a time accurate, cell centered finite volume method in solving the Navier–Stokes equations governing the 3D unsteady flow dynamics in a conceptual model of an multiply constricted arterial vessel. In comparison to the pressure drop across a single stenosis, nearly a 50% increase in the late systolic and early diastolic pressure drops has been observed across the two mild constrictions when they are spaced within a distance of S≤4. When S≤4, more than a 25% reduction in the peak systolic wall shear stress (WSS) on the downstream constriction is noted.
Journal: Biorheology, vol. 39, no. 3-4, pp. 351-357, 2002
