Numerical study on post-stenotic dilatation

Issue title: Memorial Issue in Honor of Bun’ichi Tamamushi

Guest editors: Syoten Oka and Eiichi Fukada

Article type: Research Article

Authors: Kawaguti, M. | Hamano, A.

Affiliations: Department of Physics, Keio University, Hiyoshi, Yokohama, Japan

Note: [] Accepted by: Editor S. Oka

Abstract: Steady flows and pulsatile flows of a Newtonian fluid through a channel with a rectangular hump were numerically studied as a two-dimensional model of blood flow in a constricted artery. From the numerical calculation, it was shown that one of the hydrodynamic causes of endothelial lesion of artery and post-stenotic dilatation can be found in the large temporal variation of shear stress behind a constricted portion of artery. Local maximum of the pressure there can be seen as secondary factor for the post-stenotic dilatation.

Keywords: Stenosis, Constriction, Post-stenotic dilatation, Pulsatile flows

DOI: 10.3233/BIR-1983-20508

Journal: Biorheology, vol. 20, no. 5, pp. 507-518, 1983