Affiliations: Division of Orthopaedics and Rehabilitation, San Diego Veterans Administration Medical Center, and University of California, San Diego, La Jolla, California 92093, USA
Note: [*] Guest Professor, Faculty of Engineering, Kobe University, Kobe, Japan, July, 1981 through January, 1982
Note: [] Accepted by: Editor-in-Chief A.L. Copley
Abstract: The primary goal of this investigation is to study whether soft tissue homeostatic responses secondary to decrease or increase in physiological stress levels and range of motion are a change of mechanical properties or a change of mass, or both. Two experimental animal studies are presented. One is a stress and motion deprivation study by immobilization of a rabbit knee, and the other is an increase in stress and motion study by running exercise of the miniature swine. The findings are that changes in stress and motion significantly altered the tissue properties as well as mass in the case of ligaments and digital extensor tendons. Whereas, no significant changes in properties and mass were detected for the digital flexor tendons. Possible mechanisms of the difference in tissue responses to stress and motion are discussed, and nonlinear relationships between stress and tissue remodeling are suggested.
Keywords: tissue homeostasis, immobilization, exercise, biomechanical properties, mass
DOI: 10.3233/BIR-1982-19302
Journal: Biorheology, vol. 19, no. 3, pp. 397-408, 1982
