Affiliations: [a] Pamukkale University, Faculty of Medicine, Department of Physiology, Kinikli, Denizli, Turkey | [b] Pamukkale University, Physical Therapy and Rehabilitation Highschool, Kinikli, Denizli, Turkey | [c] Gedik University, Sport Sciences Faculty, Istanbul, Turkey | [d] Suleyman Demirel University, Department of Emergency Medicine, Isparta, Turkey
Correspondence:
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Address for correspondence: Emine Kilic-Toprak, PhD, Pamukkale University, Faculty of Medicine, Department of Physiology, Kinikli, 20070 Denizli, Turkey. Tel.: 0090 258 296 17 02; Fax: 0090 258 296 24 33; E-mail: pt_emine@yahoo.com, ektoprak@pau.edu.tr
Abstract: BACKGROUND:Isokinetic exercise is used to reduce strength imbalance and to enhance performance. OBJECTIVE:The aim of this study was to investigate the acute effects of a single bout of eccentric isokinetic exercise on hemorheology (erythrocyte deformability and aggregation), total oxidant/antioxidant status (TOS/TAS) and oxidative stress index (OSI) in active individuals. METHODS:The study comprises 11 active, healthy, male subjects (mean age of 19.45 ± 0.31 years, BMI 22.05 ± 0.51 kg/m2). They performed single, unilateral eccentric contractions of knee flexors and extensors with dominant leg on a dynamometer. Isokinetic hamstring, quadriceps strength were recorded at eccentric (30, 120° s−1) angular velocities. Eight active age-matched healthy male subjects were included as a control group, who did not receive exercise. Blood samples were obtained before, immediately after and two days after the exercise session. Hemorheological parameters were measured by an ektacytometer. TOS/TAS were determined using a commercial kit. RESULTS:A session of eccentric isokinetic exercise did not affect erythrocyte deformability and oxidative stress indices, whereas red blood cell (RBC) aggregation was increased initially and returned to pre-exercise levels after two days following exercise. CONCLUSION:Our results suggest that, increased RBC aggregation following an acute bout of isokinetic exercise may result in increased plasma skimming that augments tissue perfusion and clearance of metabolites within a period of two days following exercise.
Keywords: Hemorheology, oxidative stress, eccentric exercise, red blood cell aggregation
DOI: 10.3233/BIR-180175
Journal: Biorheology, vol. 55, no. 1, pp. 15-24, 2018
