Affiliations: Department of Applied Bioscience, Tokyo University of
Agriculture, Sakuragaoka, Setagaya, Tokyo 156-8502, Japan
Note: [] Address for correspondence: Shaw Watanabe, Tokyo University of
Agriculture, 1-1-1, Sakuragaoka, Setagaya, Tokyo 156-8502, Japan. Fax: +81 3
5477 7222; E-mail: swatanab@nodai.ac.jp
Abstract: Dietary factors that influence platelet aggregation have not been
fully clarified in humans. 63 Japanese women, aged 40–70 years old, completed
one-day weighted dietary records, and received physical and laboratory
examinations. Platelet aggregation was measured by 1.0 and
3.0 μM ADP induction. The results were analyzed with
special reference to fatty acids. The short and medium chain fatty acid intake
showed negative correlation with maximum percent of platelet aggregation
induced by 1.0 μM ADP. Short and medium chain fatty acids
in this study were mostly derived from milk and dairy products. Importance of
short and medium chain fatty acid intake on platelet aggregation requires
further study for prevention of cardiovascular diseases.
Keywords: platelet aggregation, fatty acid, human nutrition, epidemiology
Journal: BioFactors, vol. 22, no. 1-4, pp. 205-210, 2004
