Affiliations: Division of Food Science, Incorporated Administrative
Agency, National Institute of Health and Nutrition, 1-23-1 Toyama, Shinjuku-Ku,
Tokyo 162-8636, Japan. E-mail: jnagata@nih.go.jp | The Nisshin Oillio Ltd., Tokyo 104-8285, Japan
Note: [] Corresponding author
Abstract: The physiological activity and effect on lipid metabolism of four
types of structured lipids (SLs), that contain caprylic acid (C8) and either
eicosapentaenoic (EPA) or docosahesaenoic acid (DHA), were evaluated in male
Wistar rats fed experimental diets containing 7% (wt %) of each SL and 3% (wt
%) soybean oil for 28 days. Control rats were fed a diet containing 10% (wt %)
soybean oil. The relative perirenal adipose tissue weights of rats fed D-8-8
and 8-D-8 diets were significantly lower than those of other groups. We
observed significantly lower serum cholesterol concentrations in rats fed SLs
than those of control group over experimental period. The serum lipids
concentrations in rats fed diets containing SLs were significantly lower P <
0.05) than those of soybean oil group. The fatty acid compositions of WAT did
not reflect the structural differences in the triglyceride. These results
suggest that the physiological effects of the SLs used in this study were due
to the fatty acids rather than the structural specificity. Therefore, further
study will be needed to ascertain the most desirable structural
configuration.
Keywords: structured lipid, rats, lipid profiles
Journal: BioFactors, vol. 22, no. 1-4, pp. 157-160, 2004
